Archived Projects of the TBINDC Registry by Researchers Last Name
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15 archived projects available at this time for James F. Malec, Ph.D.
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| Long-term outcomes by methods of postacute rehabilitation pathway among adult persons following TBI compared to orthopedic controls. | ||
| Abstract: Goals of this study are: (1) determination of the long-term outcomes of TBI at all levels of initial injury severity in comparison to an orthopedic control group among a broad age range of adults; (2) determination of outcomes by type of rehabilitation pathway in a Moderate-Severe TBI group; (3) determination of similarities of results to National TBIMS Database; (4) maintenance of optimal clinical care through an internal case coordination system; (5) Development of a reliable and valid global outcome index (Mayo-Portland Adaptability Inventory) of postacute rehabilitation outcome.... more | ||
| Investigators: | Malec J, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Outcome as a function of apoliprotein E genotype | ||
| Abstract: Differences in recovery from TBI for persons with similar levels of severity of injury is unexplained; genetic vulnerability to traumatic injury of neural tissue and support structures may offer an explanation. Participants from each of the three defined age groups with moderate-severe TBI will be divided into two additional groups: (1) those with and (2) those without an E allele. Differences in outcome among these two apo E groups will be evaluated using a 2x3 analysis of variance with apo E status as one factor and age group as the second factor. The goal of this study is to determine the impact of apolipoprotein E genotype on TBI outcome and its potential role in rehabilitation planning. ... more | ||
| Investigators: | Malec J, Smith G, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Long-term Outcome Prediction | ||
| Abstract: Although severity of initial injury has been shown to have some value in predicting long term outcome of TBI, other variables (e.g. personality, family and social support, initial indicators of impairment and disability) may also have significant predictive power. These other factors merit further investigation and may have greater predictive power in combination. Potential outcome predictors will be evaluated for persons of all ages including the elderly.... more | ||
| Investigators: | Malec J, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Prediction of Postacute Rehabilitation Outcome by MPAI Disability Rating | ||
| Abstract: No psychometrically-sound assessment tools are currently available for evaluating persons for postacute brain injury rehabilitation. The Mayo-Portland Adaptability Inventory (MPAI) may be such a measure. Goals of the study are: (1) evaluation of the MPAI as a predictor of treatment outcome and level of treatment required; (2) evaluation of measures of self-awareness of deficit and rehabilitation process as predictors of treatment outcome and level of treatment required; (3) determination of the value of other treatment outcome predictors.... more | ||
| Investigators: | Malec J, Brown A, Moessner A, Kendall K | view full details |
| Lead Center: | Mayo Medical Center | |
| Effectiveness of Specialized Vocational Services for persons with TBI | ||
| Abstract: This study will examine the effectiveness of specialized vocational services for persons with acquired brain injury. An optimally served group (those less than 1 year post-injury) will be compared to an active control group (those more than one year post-injury). The late intervention group will also serve as their own controls since they have a long baseline of lack of vocational success. Goals of the study are: (1) determination of the effectiveness of specialized vocational services for employment after TBI in terms of vocational placement, community integration, and economic factors; and (2) determination of the effects of time since injury on the effectiveness of specialized TBI vocational services.... more | ||
| Investigators: | Malec J, Degiorgio L, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Effect of Disability Rated with the MPAI on VR after TBI | ||
| Abstract: The effect of initial level of disability (pre-intervention MPAI score) and of MPAI subscales on vocational outcome will be assessed on each outcome measure through multiple regression and multiple logistic regression analyses. The interaction of early vs. late group and initial MPAI score will also be examined. The potential impact on outcome variables of other predictor variables and their interaction with treatment group singly and potentially in combination will be conducted on an exploratory basis using similar multiple regression analyses. The goal of the study is to determine the effect of initial level of disability as measured by the MPAI on vocational outcome following specialized vocational services after TBI.... more | ||
| Investigators: | Malec J, Degiorgio L, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Social support as a Moderator of Violent Behavior following TBI | ||
| Abstract: Violent behavior may both result in traumatic brain injury and may result from traumatic brain injury. Identification of factors (such as, social support) that may mitigate the occurrence of violent behavior as a result of traumatic brain injury would be of value. Goals of this project are: (1) determination of the prevalence of violent behavior following injury among persons at all levels of TBI in contrast to an orthopedic control group; (2) identification of predictors of violent behavior following TBI with particular attention to type and extent of social support as a moderating variable of violent behavior.... more | ||
| Investigators: | Malec J, Moessner A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Effect of disability rated with the vocational assessment protocol on VR after TBI | ||
| Abstract: The effect of initial level of disability (pre-intervention Vocational Assessment Protocol scores) on vocational outcome will be assessed on each outcome measure through multiple regression and multiple logistic regression analyses. The interaction of early vs. late group and initial Vocational Assessment Protocol scores will also be examined. The goal of this study is to determine the effect of initial level of disability as measured by the Vocational Assessment Protocol on vocational outcome following specialized vocational services after TBI.... more | ||
| Investigators: | Malec J, Degiorgio L, Moessner A, Brown A, Thomas D | view full details |
| Lead Center: | Mayo Medical Center | |
| Pre- post Comparison of Two Models of TBI Services: Comprehensive Day Treatment and Limited Outpatient Rehabilitation | ||
| Abstract: Further evaluation is needed of the effectiveness of various methods and intensities of postacute brain injury rehabilitation. This study will evaluate the effectiveness of two levels (or pathways) of outpatient brain injury rehabilitation. Goals of the study are: (1) determination of the effectiveness of two alternative TBI service delivery models; and (2) determination of the long-term outcomes of postacute rehabilitation interventions.... more | ||
| Investigators: | Malec J, Brown A, Moessner A, Kendall K | view full details |
| Lead Center: | Mayo Medical Center | |
| Controlled study of cost/utilization of services by injury severity | ||
| Abstract: Accurate estimates of costs of TBI among adults are not available, emphasizing the need for this priority in TBIMS research. Medical costs alone of TBI have been estimated to be over $4 billion annually. Previous TBI Model Systems data indicate the extent and cost of rehabilitation services is greater for elderly than younger adults with TBI. The goals of this project are: (1) determination of long-term cost/utilization of medical, rehabilitation, social, and community services by persons with TBI across the adult age span at all levels of initial injury severity in comparison to an orthopedic control group; (2) determination of cost/utilization of medical, rehabilitation, social, and community services by persons with TBI by type of... more | ||
| Investigators: | Brown A, Malec J, Moessner A, Leibson C | view full details |
| Lead Center: | Mayo Medical Center | |
| Costs of TBI: A Model Based on Incidence and Prognosis | ||
| Abstract: In addition to a dearth of epidemiological data on TBI, population-based studies of costs of care are also lacking. The immediate cost impact of TBI will be estimated by examining the average medical costs accrued by each subject for the year prior to injury compared to the costs accrued for the year following injury on a month-by-month basis. Goals of this study are: (1) development of an incidence-based model that encompasses the direct and indirect costs of TBI; (2) comparison of direct and indirect costs of TBI resulting from violent vs. nonviolent causes.... more | ||
| Investigators: | Leibson C, Brown A, Malec J | view full details |
| Lead Center: | Mayo Medical Center | |
| Validation of a clinical attention rating scale | ||
| Abstract: Attention deficits are commonly reported after traumatic brain injury. A variety of laboratory measures have been used to study attention and assess its response to treatment. However, this approach is seldom feasible for clinical use. Rating scales of attention-related behavior have been developed for other clinical situations (e.g., ADHD), but no well-validated scale exists for use in TBI. This project seeks to assess the inter-rater reliability and factor structure of an observational rating scale of attention developed for use in TBI. Research participants are individuals admitted to acute rehabilitation after TBI, who are at least Rancho Los Amigos level IV, and are undergoing no changes in psychoactive drugs. Such individuals are... more | ||
| Investigators: | Whyte J, Hart T, Bode R, Malec J, Millis S, Thompson R, Hammond F | view full details |
| Lead Center: | Moss Rehabilitation Research Institute | |
| Collaborating Centers: | Virginia Commonwealth University/Medical College of Virginia, Carolinas Rehabilitation, Kessler Medical Rehabilitation Research and Education Corporation, Methodist Rehabilitation Center, Spaulding Rehabilitation Hospital, Mayo Medical Center | |
| Epidemiology of TBI in Olmsted County, MN | ||
| Abstract: Current population-based studies of the epidemiology of TBI at various level of severity are limited. Additional data, particularly regarding very long term outcomes, would be of value. Through a population-based study of all cases of TBI receiving medical attention in Olmsted County, MN from 1985-2000, this study will pursue the goals of: (1) determination and comparison of the incidence of TBI due to violent vs. nonviolent cause; (2) comparison of outcomes at one and two years and up to 15 years post-injury from violent vs. nonviolent injuries by injury severity; (3) comparison of obtained data with National TBIMS Database and other available studies.... more | ||
| Investigators: | Leibson C, Brown A, Malec J | view full details |
| Lead Center: | Mayo Medical Center | |
| Gait and balance disturbance in persons with good recovery after TBI | ||
| Abstract: Many individuals who have suffered even a mild TBI and complain of instability that may not be apparent to an observer have objective finding to support their complaints. In addition, the findings imply that trauma (e.g., by displacement of the canaliths and perhaps injury to the peripheral vestibular system (as evidenced by the caloric testing results) is a frequent cause for these deficits and that a significant fraction of these subjects (3/10 in our study) will have an easily rectifiable cause of their complaints. Vestibular testing in patients with even subtlest complaints of imbalance following TBI is warranted. The presence of neurocognitive abnormalities warrants further exploration of the association between vestibular and... more | ||
| Investigators: | Basford J, Chou L, Kaufman K, Brey R, Malec J, Moessner A, Walker A, Brown A | view full details |
| Lead Center: | Mayo Medical Center | |
| Relationship of early neuropsychological functioning with supervision needs one year after traumatic brain injury | ||
| Abstract: A recently completed study employing TBI Model Systems data revealed that cognitive deficits at one year after TBI are associated with a higher need for supervision at that time, among individuals who do not have significant motor deficits. The present study will examine the relationship between cognitive deficits early in the course of recovery (using the neuropsychological evaluation completed during inpatient rehabilitation) and supervision needs at one year after the trauma. The goal is to establish (if possible) guidelines for clinicians to follow in advising survivors and family members about potential supervision needs in the future. ... more |
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| Investigators: | Novack T, Baflos J, Hart T, Millis S, Hanks R, Rosenthal M, Sherer M, Malec J, Bell K | view full details |
| Lead Center: | University of Alabama | |
| Collaborating Centers: | Moss Rehabilitation Research Institute, Kessler Medical Rehabilitation Research and Education Corporation, Rehabilitation Institute of Michigan, Methodist Rehabilitation Center, Mayo Medical Center, University of Washington | |
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15 archived projects available at this time for James F. Malec, Ph.D.
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