Projects of the TBINDC Registry by Research Center
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22 projects available at this time for Carolinas Rehabilitation
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| Use of Injury Severity Variables in Determining Disability and and Community Integration after Traumatic Brain Injury | ||
| Abstract: Much is known about the short-term outcome of individuals acutely hospitalized for traumatic brain injury (TBI) but little is known about the longer-term outcomes and the variables that may predict these outcomes. This study describes the relationship of injury severity measures to one-year outcome for 120 patients hospitalized with TBI at a Level I Trauma Center, as measured by the Disability Rating Scale (DRS) and Community Integration Questionnaire (CIQ). The Glasgow Coma Scale, Revised Trauma Score, Injury Severity Score and The Combined Trauma Score Injury Severity Score (TRISSRTS) were predictive of one-year outcome in this cohort. ... more | ||
| Investigators: | Wagner A, Hammond F, Sasser H, Wiercisiewski D, Norton H | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Duration of Post-traumatic Amnesia as a Functional Outcome Predictor in Traumatic Brain Injury | ||
| Abstract: Levin, et al. studied the relationship of post-traumatic amnesia (PTA) to outcome, and reported that those with PTA > 2 weeks had severe disability based on the Glasgow Outcome Scale (GOS). This study investigated the relationship of coma and PTA duration (as measured by serial administration of the Galveston Orientation Amnesia Test) to the GOS and Disability Rating Scale... more | ||
| Investigators: | Nguyen V, Wiercisiewski D, Hammond F, Norton H | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Illicit Drug Use Over Time Following Traumatic Brain Injury | ||
| Abstract: Reported drug use at Years 1 and 2 following traumatic brain injury (TBI) is 6 to 8%, compared to 29% premorbidly. How drug use responses change over time in the same group is not known. This study investigates patterns of reported drug use and follow-up for individuals with TBI who received inpatient rehabilitation, and who were questioned annually about illicit drug use. The TBI Model System Database (n=1160) was used to perform a cross-sectional analysis on all successfully contacted and screened over a 10 year period. Responses to drug use at Year 1 were 37 yes, and 333 no, with no significant difference in yes/no responses across the years. However, analysis of the positive responses revealed those reporting drug use in Year 1 had... more | ||
| Investigators: | Hammond F, Grattan K, Sasser H, Corrigan J, Bogner J, Kreutzer J, Weintraub R, Berry J | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Collaborating Centers: | Ohio State University, Virginia Commonwealth University/Medical College of Virginia | |
| The Efficacy and Utility of a Community Transition Coordinator in Improving Community Integration, Quality of Life, and Return to Work: A Randomized, Controlled Clinical Trial. | ||
| Abstract: Survivors of TBI and their families are confronted with many new challenges. After being guided through many sudden life changes by trained professionals during inpatient rehabilitation, the transition to the community inevitably poses numerous obstacles that must often be faced with minimal outside assistance. This study investigates the utility of a community transition coordinator (CTC) assigned to adults with TBI in a randomized, controlled trial with the goal of developing a replicable model of community reintegration that provides linkages to services after discharge from comprehensive acute rehabilitation inpatient services. The comparison group receives standard post-rehabilitation services without a CTC.... more | ||
| Investigators: | Hammond F, Coghill J, Norton H | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Impact and Efficacy of Electronic Personal Organizer versus Standard Memory Notebook on Memory, Daily function and Quality of Life | ||
| Abstract: Memory impairment is one of the most common complications of TBI, posing significant barriers to the everyday life, work, school, and quality of life. Standard practice involves memory strategies incorporating the use of a memory notebook. Increasingly, the general public has been using electronic personal organizers (EPOÂ’s). The EPO has all the features of the standard notebook as well as offering alarms and backup options, are compact, require no extra supplies, and are easy to update. This randomized, controlled study compares an EPO to the standard memory notebook in terms daily function.... more | ||
| Investigators: | Hammond F, Grattan K, Norton H, Gosney G, Baker G, Hill J | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| The Value of Trauma Scores: Predicting Discharge after Traumatic Brain Injury | ||
| Abstract: The relationship of acute injury severity measures to discharge disposition was studies for 378 adults consecutively hospitalized with TBI at a Level I Trauma Center. The Combined Trauma Score Injury Severity Score (TRISSRTS) was predictive of discharge to home or acute rehabilitation versus nursing home or death. Excluding those who died or discharge to a nursing home, the Revised Trauma Score and Injury severity Score were predictive of discharge to home versus inpatient rehabilitation. Testing these 2 predictive models on a sample of 4,625 patients with TBI treated at the same facility revealed sensitivities of 98% and 94% respectively... more | ||
| Investigators: | Wagner A, Hammond F, Grigsby G | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Return to Productive Activity After Traumatic Brain Injury: Relationship with Measures of Disability, Handicap, and Community Integration | ||
| Abstract: Return to productive activity (RTPA) is considered a major outcome marker for TBI. One hundred and five respondents from a cohort of 378 adults hospitalized at a Level I Trauma Center with TBI were studied to describe the rate of RTPA and associated factors. There was 67% RTPA. Factors found to be associated with successful RTPA were educational level, psychiatric history, violent mechanism of injury, discharge status after acute hospitalization, prior alcohol and drug use, and injury severity, as well as the Disability Rating Scale and the Community Integration Questionnaire at one year post-injury... more | ||
| Investigators: | , Hammond F, Sasser H, Wiercisiewski D | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| The Prognosis Utility of Pre-Injury, Injury-Related, and Post-Injury Factors in Predicting Outcome in terms of Function, Community Integration, and Quality of Life | ||
| Abstract: Abstract: Recovery from TBI involves multiple processes occurring at different times post-injury. Outcome studies have been performed extensively, predominately utilizing the Glasgow Outcome Scale (GOS). The GOS is limited in its measure of outcome by its broad categories; included within a single category may be a wide differential in burden of care, cost, functional level, and social interaction. Studies assessing the relationship of potentially predictive factors to functional outcomes and quality of life are lacking. This study investigates the relationship of premorbid, injury-related and post-injury related factors to function and quality of life. Primary research hypotheses: 1)Functional outcomes and perceived quality of life at... more |
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| Investigators: | Hammond F, Norton H, Phillips V, Johnston M | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Collaborating Centers: | Emory University/Shepherd Center, Kessler Medical Rehabilitation Research and Education Corporation | |
| Post-traumatic Depression as a Complication of Violence Induced TBI Versus Non-violence Induced TBI: Implications on treatment, interventions, cost, and long-term outcomes. | ||
| Abstract: Depression is a well-established complication of TBI, with reported incidence of less than 10% to 77%. However, previous studies have been limited by small, unrepresentative samples. This study investigates the incidence, time-course, outcome, and measurement of post-traumatic depression in those with TBI who survive and are admitted to acute inpatient rehabilitation.... more | ||
| Investigators: | Hammond F, Babin P, Grattan K, Norton H, Johnston M, Miller M, Kreutzer J, Black K | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Collaborating Centers: | Rehabilitation Institute of Michigan, Kessler Medical Rehabilitation Research and Education Corporation, Emory University/Shepherd Center, Virginia Commonwealth University/Medical College of Virginia | |
| Serial Casting Versus Ultrasound with Weight Bearing for the Treatment of Equinovarus Contractures in the Individual with Acute TBI: Comparison of Efficacy and Cost | ||
| Abstract: Plantar flexion contractures are a common complication of TBI. Multiple treatment methods are available for increasing joint range of motion (ROM). Serial casting and ultrasound combined with a static stretch are two conservative methods of treatment for plantar flexion contractures known to increase dorsiflexion ROM. However, studies have not compared the effectiveness and cost of serial casting versus ultrasound/static stretch in increasing dorsiflexion ROM. This is a randomized, controlled study comparing the efficacy and cost associated with these two methods... more | ||
| Investigators: | Hammond F, Lang E, LaBarbera J, Bucklew S, Norton H, Burke D, Flanagan S, Rupright J | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Collaborating Centers: | Spaulding Rehabilitation Hospital, University of Missouri | |
| Factors Influencing Cost of Care and Resource Utilization for Individuals with TBI Participating in Acute Inpatient Rehabilitation: The Relationship to Outcome | ||
| Abstract: Difficult decisions regarding the appropriate allocation of services are continually needed in order to control health care costs. In the case of TBI, such decisions must focus on optimizing function and quality of life while minimizing the costs to society and survivors. It is important to demonstrate the efficacy and cost-effectiveness of treatment interventions and service delivery models. Numerous studies have investigated the direct overall cost of acute medical and rehabilitation hospitalization. However, studies regarding the costs and effectiveness of particular treatment strategies utilized in a comprehensive rehabilitation programs and post-acutely are lacking. This study investigates potential predictors of cost... more | ||
| Investigators: | Hammond F, Grattan K, McDeavitt J, Handy-Williams B, Norton H, Phillips V, Johnston M | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Collaborating Centers: | Emory University/Shepherd Center, Kessler Medical Rehabilitation Research and Education Corporation | |
| Utilization of Rehabilitation Resources in Pediatric Trauma Patients With and Without Head Injury | ||
| Abstract: Rehabilitation services after pediatric trauma helps reduce morbidity. However, a better understanding of how these services are utilized is needed. Studies of acute care disposition have suggested that, after controlling for injury and impairment severity, there is a correlation between receipt of inpatient rehabilitation and the availability of rehabilitation resources. This prospective study of 2,319 trauma patients under 16 years of age consecutively admitted to a Level I Trauma Center examined rehabilitation service receipt during and after discharge where availability of rehabilitation services remained constant. The sample included 67.4% with minor injuries and 21.7% with major trauma as defined by the Injury Severity Score. Of... more | ||
| Investigators: | Kolaski K, Sasser H, Grattan K | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Gender Associated Differences in Outcome after Traumatic Brain Injury | ||
| Abstract: The sparse literature on gender and TBI suggest reasons to expect gender-based outcome differences. One hundred twenty persons from a cohort of 378 adults admitted with TBI to a Level I trauma Center were studied to examine the relationship between gender and outcome. In this sample, women were predominately older than the men (80% men and 58% women were <50 years old). Factors significantly different by gender included age, payor, arrest history, pre-and post-injury employment, and injury severity. Female gender was a significantly predictive of poorer total DRS and CIQ Productivity even after adjusting for other factors, but not of total CIQ Total, Home and Social scores. This suggests that TBI may be influenced by gender, and that... more | ||
| Investigators: | Wagner A, Hammond F, Sasser H, Wiercisiewski D | view full details |
| Lead Center: | Carolinas Rehabilitation | |
| Mortality and Life Expectancy After TBI Rehabilitation | ||
| Abstract: Abstract from Project Phase I - Objective: To investigate mortality, life expectancy, risk factors for death, and causes of death in individuals with traumatic brain injury (TBI). Methods: Retrospective cohort study utilizing data from the TBI Model Systems National Database, the Social Security Death Index and death certificates. Participants: 2,178 individuals with TBI completing inpatient rehabilitation in one of 15 National Institute on Disability and Rehabilitation Research-funded TBI Model Systems of care between 1988 and 2001. Results: Individuals with TBI were twice as likely to die compared to individuals in the general population of similar age, gender and race, resulting in an estimated average life expectancy reduction of 7... more | ||
| Investigators: | Harrison-Felix C, Whiteneck G, Devivo M, Hammond F, Jha A | view full details |
| Lead Center: | Craig Hospital | |
| Collaborating Centers: | Carolinas Rehabilitation, Emory University/Shepherd Center, Mayo Medical Center, Ohio State University, University of Alabama, Oregon Health Sciences University, University of Missouri, Moss Rehabilitation Research Institute, Rehabilitation Institute of Michigan, Spaulding Rehabilitation Hospital, Virginia Commonwealth University/Medical College of Virginia, Santa Clara Valley Medical Center, University of Washington | |
| A Prospective Observational Study of Screening and Prophylaxis for Deep Vein Thrombosis in Survivors of Traumatic Brain Injury During Inpatient Rehabilitation | ||
| Abstract: During the period of acute rehabilitation for traumatic brain injury (TBI), the development of deep vein thrombosis (DVT) is a significant complication that increases morbidity and mortality. Pulmonary embolism (PE) is one of the most ominous, and frequently life-threatening, complications that occur during TBI rehabilitation. TBI patients often sustain concomitant multiple trauma and have cumulative risk factors for DVT. Because these TBI patients are usually maintained at bed rest during their acute hospitalization, they are at increased risk for existing DVT to embolize when they enter the rehabilitation setting and resume mobility. Prior to initiating this study, a practice survey was distributed to the 16 rehabilitation centers of... more | ||
| Investigators: | Carlile M, Diaz-Arrastia R, Mysiw W | view full details |
| Lead Center: | North Texas Traumatic Brain Injury Model System | |
| Collaborating Centers: | Carolinas Rehabilitation, JFK Johnson Rehabilitation Institute, Mayo Medical Center, Mount Sinai School of Medicine, Santa Clara Valley Medical Center, Methodist Rehabilitation Center, Ohio State University, University of Alabama, University of Pittsburgh | |
| Brain injury severity as measured by the Glasgow Coma Scale & its influence on outcome as measured by Disability Rating Scale at acute rehabilitation discharge and long term follow-up after severe TBI | ||
| Abstract: This study will compare outcomes among those with severe injuries to determine how they differ at discharge from rehabilitation and at 1, 5 and 10 years after injury. The data from the model system national database will be reviewed to determine how the patterns and ultimate recovery differ by Glasgow Coma Scale (GCS) score. Severity of injury will be measured by GCS scores in the emergency room. Outcome will be measured by the Disability Rating Scale (DRS).... more | ||
| Investigators: | Burke D, Hammond F, Rosenthal M, Glenn M, Meythaler J, Jacob L | view full details |
| Lead Center: | Spaulding Rehabilitation Hospital | |
| Collaborating Centers: | Carolinas Rehabilitation, University of Alabama | |
| Subjective Well-being in the First Two Years Following Traumatic Brain Injury | ||
| Abstract: Purpose: Examine predictors of life satisfaction one and two years post-injury. Design: Prospective, longitudinal study of patients with TBI followed at one and two years post-injury. Replication of a single center study using data from the TBI Model Systems dataset. Univariate regression models will be calculated first. Those variables that account for at least 1% of variance will be included in subsequent stepwise linear regression models. Current status: Data has been compiled.... more |
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| Investigators: | Corrigan J, Bogner J, Hammond F, Sander A, Whiteneck G, Kreutzer J | view full details |
| Lead Center: | Ohio State University | |
| Collaborating Centers: | Carolinas Rehabilitation, The Institute for Rehabilitation and Research, Virginia Commonwealth University/Medical College of Virginia | |
| Responsiveness of the Community Integration Questionnaire (CIQ) and the Supervision Rating Scale (SRS) | ||
| Abstract: It is unknown whether the CIQ (or the SRS) is sensitive to change in S.s. This study planned to use data from other studies, where the CIQ (and/or the SRS) is collected both before and after CI-related interventions, to assess whether these instruments are responsive to change. The study was never initiated due to lack of sufficient available data.... more | ||
| Investigators: | Goldstein R, Hammond F | view full details |
| Lead Center: | Spaulding Rehabilitation Hospital | |
| Collaborating Centers: | Carolinas Rehabilitation | |
| Family Members' and Caregivers' Emotional Well Being | ||
| Abstract: Objectives for this collaborative project include: (1) to examine the frequency and magnitude of emotional distress and depressive symptoms and the level of life satisfaction of family members and non-family caregivers as compared to clinical and non-clinical populations, and (2) to identify the relationships between caregivers' well-being and survivors' injury severity and level of functioning. Six TBI Model System centers are collecting data from family members, significant others, and friends of individuals in the National Database at either 1, 2, or 5 year follow-up. Data is collected from each caregiver only once. Measures include the Neurobehavioral Functioning Inventory (NFI) Depression subscale, the Brief Symptom Inventory-18... more | ||
| Investigators: | Kreutzer J, Marwitz J, Rapport L, Koviak C, Hammond F, Morita C, Hart T, Selleck E, Glenn M, Harrison-Felix C | view full details |
| Lead Center: | Virginia Commonwealth University/Medical College of Virginia | |
| Collaborating Centers: | Spaulding Rehabilitation Hospital, Rehabilitation Institute of Michigan, Carolinas Rehabilitation, Moss Rehabilitation Research Institute, Craig Hospital | |
| Depression after traumatic brain injury: A NIDRR model systems multi-center investigation. | ||
| Abstract: Objective: To identify the frequency and manifestations of depression after traumatic brain injury (TBI) and the factors that contribute to developing this mood disorder. Design: A prospective, nationwide, multicenter study; 17 centers supplied data from medical records and patient responses on a standardized criterion instrument. Setting: Traumatic Brain Injury Model Systems programs. Participants: A demographically diverse sample of 666 outpatients with TBI was evaluated 10 to 126 months after injury. Main Outcome Measures: Depressive symptoms were characterized with the Neurobehavioral Functioning Inventory by using the Diagnostic and Statistical Manual of Mental Disorders (4th ed; DSM-IV) diagnostic framework. Analysis of... more |
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| Investigators: | Seel R, Kreutzer J, Rosenthal M, Hammond F, Corrigan J, Black K | view full details |
| Lead Center: | Virginia Commonwealth University/Medical College of Virginia | |
| Collaborating Centers: | Rehabilitation Institute of Michigan, Kessler Medical Rehabilitation Research and Education Corporation, Carolinas Rehabilitation, Ohio State University | |
| Effect of blood alcohol level on neurpsych outcome from TBI | ||
| Abstract: 1) To resolve contradictory reports in the literature regarding adverse effects of acute blood alcohol level (BAL) on neuropsychological outcome from traumatic brain injury (TBI). 2) 459 adults with nonpenetrating TBI who were inpatients at one of 6 rehabilitation centers in the TBI Model Systems project, whose BAL had been measured at hospital arrival, and who emerged from post-traumatic amnesia (PTA) and underwent neuropsychological testing before rehabilitation discharge. 3)15 neuropsychological tests were administered after resolution of post-traumatic amnesia and at one year post-injury. 4) BAL was classified as 1) negative vs. positive and 2) intoxicated (BAL > 100 mg/dl) vs. non-intoxicated. The effect of BAL on neuropsychological... more | ||
| Investigators: | Boake C, High Jr. W, Sander A, Kreutzer J, Macciocchi S, Stringer A, Hammond F, Rosenthal M, Bogner J, Hanks R | view full details |
| Lead Center: | The Institute for Rehabilitation and Research | |
| Collaborating Centers: | Emory University/Shepherd Center, Ohio State University, Rehabilitation Institute of Michigan, Carolinas Rehabilitation, Kessler Medical Rehabilitation Research and Education Corporation, Virginia Commonwealth University/Medical College of Virginia | |
| A Collaborative National Information Center on Outcome Measurement in Brain Injury | ||
| Abstract: In order to better serve the rehabilitation community, the Center on Outcome Measurement in Brain Injury (COMBI) website and newsletter are proposed. The COMBI provides information on measures in a format that is easily accessed and understood, free of charge, objective, and comprehensive. Each measure will have online syllabi, training and testing materials (including the measure's rating form), information on scale properties, a reference listing of published studies using the measure, and a section for "Frequently Asked Questions."... more | ||
| Investigators: | Bushnik T, Wright J, Mellick D, Harrison-Felix C, Boake C, Sander A, Malec J, Sherer M, Thompson R, Novack T, Dijkers M, Bogner J, Corrigan J, Hammond F, Kreutzer J, Marwitz J, Millis S, O'Neil-Pirozzi T | view full details |
| Lead Center: | Santa Clara Valley Medical Center | |
| Collaborating Centers: | Craig Hospital, The Institute for Rehabilitation and Research, Mayo Medical Center, Methodist Rehabilitation Center, University of Alabama, Rehabilitation Institute of Michigan, Ohio State University, Carolinas Rehabilitation, Virginia Commonwealth University/Medical College of Virginia, Moss Rehabilitation Research Institute, Kessler Medical Rehabilitation Research and Education Corporation, Spaulding Rehabilitation Hospital, Mount Sinai School of Medicine | |
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22 projects available at this time for Carolinas Rehabilitation
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