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Projects of the TBINDC Registry by Research Center
UFOV Performance and Driving Ability Following Traumatic Brain Injury
Abstract: Objective: To investigate the relationship between performance on the Useful Field of View Test (UFOV) and driving performance following traumatic brain injury (TBI). Participants: 60 people with TBI referred for driving evaluation. Measures: Useful Field of View Test, as well as the Global Rating Scale and Driver Assessment Scale, both of which were developed for this study. Results: Subject performance diminished as the complexity of the UFOV subtests increased. There was a significant relationship between UFOV performance, particularly on the second subtest, and on-road driving performance. Subject age and Trail Making Test, Part B were also predictive of driving performance. Conclusions: The UFOV can be used as a screening... more
Investigators: Novack T view full
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Lead Center: University of Alabama
Development and Application of a Home Based Cognitive Stimulation Program
Abstract: Objective: Develop and evaluate the effectiveness of a cognitive stimulation program to be used by family members.

Design: Longitudinal study of people with TBI as controls or receiving the treatment.

Setting: Home environment.

Participants: 23 people with TBI receiving the treatment program in their homes, 28 people receiving standard of care without the treatment program.

Intervention: A program to promote cognitive stimulation using materials available in the home.

Outcome Measures: Mini Mental State Examination, Community Integration Questionnaire, Satisfaction with Life measured at baseline, 3 months, and 6 months. Referral to vocational rehabilitation was also monitored.

Results: Based on repeated measures ANOVA there... more
Investigators: Novack T view full
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Lead Center: University of Alabama
Validation of a Model for Evaluating Outcome Following Traumatic Brain Injury
Abstract: Structural equation modeling compared the fit of the data from two samples to a path analysis developed through clinical use and prior research. Both samples provide adequate goodness-of-fit measures to the model, supporting the validity of this model. These results show significant relationships between premorbid factors and acute injury severity and subsequent cognitive and functional status. Injury severity significantly affected cognitive and functional status, while cognitive and functional status significantly influenced one year outcome. As predicted, premorbid factors and injury severity did not significantly influence outcome.... more
Investigators: Novack T view full
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Lead Center: University of Alabama
Collaborating Centers: Mayo Medical Center, Emory University/Shepherd Center, Kessler Medical Rehabilitation Research and Education Corporation
Impairment and partial recovery of medical decision making capacity in traumatic brain injury: a six month longitudinal study
Abstract: The capacity to make decisions about medical care and financial issues is essential to independent functioning in the community. Diminished capacity in those areas has been studied in individuals with some types of brain disorder, such as dementia, but never with respect to TBI. Marson has developed objective techniques to evaluate decision-making capacity concerning medical care and finances. This project will examine the use of those instruments with a TBI population, exploring differences in capacity compared to non-injured controls as well as the change in capacity over a period of several months following TBI.... more
Investigators: Marson D view full
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Lead Center: University of Alabama
Self-Inflicted versus Other-Inflicted Traumatic Brain Injury: Risk Factors and Outcomes
Abstract: Abstract: Intentionally inflicted traumatic brain injury (TBI), such as those due to violence, has been a recent focus of this study. People with intentional injuries can be separated into those with self-inflicted (SI) versus other-inflicted (OI) injuries. Although there has been speculation that those with SI injuries may experience different outcomes than other people with TBI, the issue has not been examined objectively. Among 240 subjects in a prospective study, 35 experienced OI injures, usually in assaults, and 9 SI injures, usually from gunshot wounds. The groups did not differ in terms of age, education, marital status, alcohol or drug history, presence of alcohol on admission, employment at the time of injury, total... more
Investigators: Novack T, Bush B, Canupp K, Glen E, Alderson A view full
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Lead Center: University of Alabama
Intentional versus Unintentional Traumatic Brain Injury: Risk Factors and Outcomes
Abstract: Purpose: This study examined potential differences between people who have experienced intentional vs unintentional traumatic brain injury (TBI). Subjects: Subjects with unintentional injury (N=194), obtained mostly in crashes, were compared to 44 people with intentional injuries, obtained mostly in assaults, in terms of demographic information, injury factors, and outcome. Setting: Large medical center with acute rehabilitation. Measures: Functional Independence Measure (FIM), Disability Rating Scale (DRS), Community Integration Questionnaire. Results: T-tests did not reveal differences between the groups in age, education, Glasgow Coma Score, total Functional Independence Measure (FIM) scores at rehabilitation admission and... more
Investigators: Novack T, Bush B, Meythaler J, Canupp K, Alderson A view full
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Lead Center: University of Alabama
Collaborating Centers: Methodist Rehabilitation Center
Development of Participation Measures for People with Traumatic Brain Injury
Abstract: There is no general agreement in the field regarding a reliable and valid objective measure of community participation after TBI. This study will use a multi-center, prospective, cohort design to evaluate participation items pooled from four currently used tools: the Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF); the Community Integration Questionnaire Version 2 (CIQ-2); the Participation Objective-Participation Subjective (PO-PS) section of the Living Life After TBI (LLATBI); and the Mayo-Portland Participation Index (M2PI). The primary objectives of this study are to: 1) evaluate internal consistency, concurrent validity, and item/scale structure of current measures of community participation after TBI; and 2)... more
Investigators: Whiteneck G, Bushnik T, Cicerone K, Corrigan J, Bogner J, Dijkers M, Gordon W, Hart T, Malec J, Novack T view full
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Lead Center: Craig Hospital
Collaborating Centers: University of Alabama, Santa Clara Valley Medical Center, Mayo Medical Center, Kessler Medical Rehabilitation Research and Education Corporation, Mount Sinai School of Medicine, Ohio State University, Moss Rehabilitation Research Institute
Feasibility of administration of a brief neuropsychological battery for use during acute inpatient rehabilitation after TBI
Abstract: Previous investigations have studied the association of early neuropsychological test performance with late outcome in patients who were initially evaluated during inpatient rehabilitation. However, in these previous investigations, neuropsychological test findings have been confounded with patient injury severity. Neuropsychological assessment was performed at resolution of PTA and PTA duration is a well-recognized index of injury severity. Clinical experience would suggest that a patient who reaches a given level of neuropsychological functioning at one month post injury will have a better long term outcome than another patient who takes 3 months to reach the same level of neuropsychological functioning. By basing timing of testing... more
Investigators: Kalmar K, Giacino J, Novack T, Sherer M, Nakase-Thompson R, Frol A, Hanks R, Millis S, Gordon W, Ricker J view full
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Lead Center: JFK Johnson Rehabilitation Institute
Collaborating Centers: University of Alabama, Methodist Rehabilitation Center, North Texas Traumatic Brain Injury Model System, Rehabilitation Institute of Michigan, Mount Sinai School of Medicine, University of Pittsburgh
Brain injury severity as measured by the Glasgow Coma Scale & its influence on outcome as measured by Disability Rating Scale at acute rehabilitation discharge and long term follow-up after severe TBI
Abstract: This study will compare outcomes among those with severe injuries to determine how they differ at discharge from rehabilitation and at 1, 5 and 10 years after injury. The data from the model system national database will be reviewed to determine how the patterns and ultimate recovery differ by Glasgow Coma Scale (GCS) score. Severity of injury will be measured by GCS scores in the emergency room. Outcome will be measured by the Disability Rating Scale (DRS).... more
Investigators: Burke D, Hammond F, Rosenthal M, Glenn M, Meythaler J, Jacob L view full
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Lead Center: Spaulding Rehabilitation Hospital
Collaborating Centers: Carolinas Rehabilitation, University of Alabama
Mortality and Life Expectancy After TBI Rehabilitation
Abstract: Abstract from Project Phase I - Objective: To investigate mortality, life expectancy, risk factors for death, and causes of death in individuals with traumatic brain injury (TBI). Methods: Retrospective cohort study utilizing data from the TBI Model Systems National Database, the Social Security Death Index and death certificates. Participants: 2,178 individuals with TBI completing inpatient rehabilitation in one of 15 National Institute on Disability and Rehabilitation Research-funded TBI Model Systems of care between 1988 and 2001. Results: Individuals with TBI were twice as likely to die compared to individuals in the general population of similar age, gender and race, resulting in an estimated average life expectancy reduction of 7... more
Investigators: Harrison-Felix C, Whiteneck G, Devivo M, Hammond F, Jha A view full
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Lead Center: Craig Hospital
Collaborating Centers: Carolinas Rehabilitation, Emory University/Shepherd Center, Mayo Medical Center, Ohio State University, University of Alabama, Oregon Health Sciences University, University of Missouri, Moss Rehabilitation Research Institute, Rehabilitation Institute of Michigan, Spaulding Rehabilitation Hospital, Virginia Commonwealth University/Medical College of Virginia, Santa Clara Valley Medical Center, University of Washington
A Collaborative National Information Center on Outcome Measurement in Brain Injury
Abstract: In order to better serve the rehabilitation community, the Center on Outcome Measurement in Brain Injury (COMBI) website and newsletter are proposed. The COMBI provides information on measures in a format that is easily accessed and understood, free of charge, objective, and comprehensive. Each measure will have online syllabi, training and testing materials (including the measure's rating form), information on scale properties, a reference listing of published studies using the measure, and a section for "Frequently Asked Questions."... more
Investigators: Bushnik T, Wright J, Mellick D, Harrison-Felix C, Boake C, Sander A, Malec J, Sherer M, Thompson R, Novack T, Dijkers M, Bogner J, Corrigan J, Hammond F, Kreutzer J, Marwitz J, Millis S, O'Neil-Pirozzi T view full
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Lead Center: Santa Clara Valley Medical Center
Collaborating Centers: Craig Hospital, The Institute for Rehabilitation and Research, Mayo Medical Center, Methodist Rehabilitation Center, University of Alabama, Rehabilitation Institute of Michigan, Ohio State University, Carolinas Rehabilitation, Virginia Commonwealth University/Medical College of Virginia, Moss Rehabilitation Research Institute, Kessler Medical Rehabilitation Research and Education Corporation, Spaulding Rehabilitation Hospital, Mount Sinai School of Medicine
A Prospective Observational Study of Screening and Prophylaxis for Deep Vein Thrombosis in Survivors of Traumatic Brain Injury During Inpatient Rehabilitation
Abstract: During the period of acute rehabilitation for traumatic brain injury (TBI), the development of deep vein thrombosis (DVT) is a significant complication that increases morbidity and mortality. Pulmonary embolism (PE) is one of the most ominous, and frequently life-threatening, complications that occur during TBI rehabilitation. TBI patients often sustain concomitant multiple trauma and have cumulative risk factors for DVT. Because these TBI patients are usually maintained at bed rest during their acute hospitalization, they are at increased risk for existing DVT to embolize when they enter the rehabilitation setting and resume mobility. Prior to initiating this study, a practice survey was distributed to the 16 rehabilitation centers of... more
Investigators: Carlile M, Diaz-Arrastia R, Mysiw W view full
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Lead Center: North Texas Traumatic Brain Injury Model System
Collaborating Centers: Carolinas Rehabilitation, JFK Johnson Rehabilitation Institute, Mayo Medical Center, Mount Sinai School of Medicine, Santa Clara Valley Medical Center, Methodist Rehabilitation Center, Ohio State University, University of Alabama, University of Pittsburgh


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Registry Dataset accessed Monday, September 25, 2006 5:54am
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