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Projects of the TBINDC Registry by Researchers Last Name
Assessing the Pattern of Fatigue, and Its Correlates During the First Two Years Post-TBI
Abstract: The prevalence of fatigue among individuals with traumatic brain injury living in the community is estimated to range between 50% and 80%. The need to clarify the contributing factors to fatigue is driven by the availability of different treatments. This longitudinal study will examine the dynamic nature of fatigue experienced by individuals with TBI in the first two years post-injury and will document whether the nature of fatigue changes within that time frame. It will assess whether factors such as concurrent medications, sleep findings, affective symptomatology, activity patterns and limitations, substance use, and neuroendocrine profiles may contribute to the changes in fatigue dimensions within the first two years post-TBI.... more
Investigators: Englander J, Bushnik T, Wright J view full
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Lead Center: Santa Clara Valley Medical Center
Association between Fatigue, Severity of Injury, Duration of Injury, and Underlying Factors
Abstract: The consequences of fatigue are many-fold and can present significant barriers to recovery. Estimates of the prevalence of fatigue among individuals with traumatic brain injury living in the community are estimated to range between 50% and 80%. This study will expand upon the current literature and correlate the fatigue experienced by individuals at least one year post-TBI, with potential contributing factors: concurrent medications, sleep patterns, endocrine findings, affective symptomatology, activity patterns and limitations, and substance use.... more
Investigators: Bushnik T, Englander J, Wright J view full
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Lead Center: Santa Clara Valley Medical Center
Five to Eleven Years Post-Injury: Impact of Late Post-Traumatic Seizures
Abstract: The impact of late post-traumatic seizures (LPTS) in addition to a traumatic brain injury (TBI) has not been well examined. This study will characterize, describe, and highlight the particular issues that individuals with TBI and LPTS may face in their daily lives. The participant pool will be drawn from individuals who participated in an earlier NIDRR-funded study examining the risk factors for the development of LPTS. These individuals are now more than seven years post-injury. It is hypothesized that individuals with TBI and LPTS will report increased disability (physical and cognitive), increased utilization of medical services, and increased supervision needs over those without LPTS. Individuals with TBI and LPTS may report higher... more
Investigators: Duong T, Bushnik T, Englander J, Wright J view full
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Lead Center: Santa Clara Valley Medical Center
Two to Four Years Post-Injury: Impact of Late Post-Traumatic Seizures
Abstract: Traumatic brain injuries account for 20% of symptomatic epilepsy in the general population and 5% of all epilepsy. The risk factors associated with the development of late post-traumatic seizures, which are defined as occurring after the first week of injury and within 2 years of injury, include age, penetrating injuries, multiple
neurosurgical procedures, severity of injury, locations of lesions, depressed skull fracture, intracranial hemorrhage, and occurrence of early PTS. This study will utilize the power of the TBI Model Systems National Database to compare and contrast the levels of impairment, disability, and participation of those who develop late post-traumatic seizures and those who do not. The two groups will be compared at... more
Investigators: Bushnik T, Wright J, Englander J view full
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Lead Center: Santa Clara Valley Medical Center
Etiology and incidence of rehospitalizations
Abstract: Objective: To investigate incidence and etiology of rehospitalizations at one and five years post traumatic brain injury.

Design: Prospective study of etiology and incidence of rehospitalizations at years 1 and 5 years postinjury. Analysis of variance and chi-square were used to identify factors relating to rehospitalization; factors included length of stay, admission and discharge functional status, payor source, medical complications, injury severity, and demographics.

Setting: Seventeen medical centers in the federally sponsored Traumatic Brain Injury Model Systems. In each setting, the continuum of care includes emergency medical services, intensive and acute medical care, inpatient rehabilitation, and a spectrum of community... more
Investigators: Kreutzer J, Marwitz J, High Jr. W, Englander J, Cifu D view full
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Lead Center: Virginia Commonwealth University/Medical College of Virginia
Collaborating Centers: The Institute for Rehabilitation and Research, Santa Clara Valley Medical Center
Incidence, risk factors, and outcomes of fecal incontinence after acute brain injury: Findings from the traumatic brain injury model systems national database
Abstract: Objective: To investigate the incidence, risk factors, and outcome in patients with fecal incontinence after acute brain injury.

Design: A retrospective study of the incidence of and risk factors contributing to fecal incontinence, and outcomes at admission to and discharge from inpatient rehabilitation and at 1-year follow-up. Setting: Medical centers in the federally sponsored Traumatic Brain Injury Model Systems (TBIMS). Participants: A total of 1013 consecutively enrolled ehabilitation inpatients from 17 TBIMS centers who were admitted to acute care within 24 hours of traumatic brain injury and seen at 1-year
postinjury between 1990 and 2000.

Main Outcome Measures: Incidence of fecal incontinence, length of coma, length of... more
Investigators: Foxx-Orenstein A, Kolakowsky-Hayner S, Marwitz J, Cifu D, Dunbar A, Englander J, Francisco G view full
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Lead Center: Virginia Commonwealth University/Medical College of Virginia
Collaborating Centers: Santa Clara Valley Medical Center, The Institute for Rehabilitation and Research
Charges and Lengths of Stay for Acute and Inpatient Rehabilitation Treatment of TBI 1990-1996
Abstract: Acute care daily charges showed almost routine increases, averaging nearly $550 per year. Conversely, lengths of stay generally showed a downward trend, with annual reductions averaging 2.25 days. Between 1990 and 1996, average daily rehabilitation charges increased each year, with the rise averaging $83 or 7%. The rise in daily rehabilitation charges was offset by corresponding decreases in lengths of stay averaging 3.65 days or 8% annually. Increases in daily charges for brain injury rehabilitation care were roughly comparable to those for general medical care prices. However, the rate of change in acute care charges was substantially greater, with annual increases averaging 10% more than national medical care prices... more
Investigators: Kreutzer J, Kolakowsky-Hayner S, Ripley D, Cifu D, Rosenthal M, Bushnik T, Zafonte R, Englander J, High Jr. W view full
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Lead Center: Virginia Commonwealth University/Medical College of Virginia
Collaborating Centers: Santa Clara Valley Medical Center, Emory University/Shepherd Center, Rehabilitation Institute of Michigan, Kessler Medical Rehabilitation Research and Education Corporation, The Institute for Rehabilitation and Research


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National Traumatic Brain Injury Live Syllabus v2.00.00
Registry Dataset accessed Monday, September 25, 2006 10:21am
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