Projects of the TBINDC Registry by Researchers Last Name
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5 projects available at this time for Stuart A. Yablon, M.D.
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| Bladder and Bowel Incontinence after Traumatic Brain Injury: Risk Factors, Prevalence, and Outcome | ||
| Abstract: A multicenter study was conducted, reviewing the incidence, risk factors, and outcome of patients with bladder (BdI) and bowel (Bol) incontinence after traumatic brain injury (TBI). Subjects were 587 patients for whom follow-up data at one-year postinjury were available. 77% of patients were incontinent at rehabilitation admission (Bdl 77.3%, Bol 76.7%). The prevalence of incontinence improves to approximately 20% (Bdl 20.3%, Bol 19.2%) by rehabilitation discharge, and 7% (Bdl 7.8%, Bol 6.3%) by one year post-injury. Continent patients were significantly more likely to be living at home at rehabilitation discharge (OR=3.2; [1.8, 5.3]) and at one year post-injury (OR=7.7; [3.9, 15.3])... more | ||
| Investigators: | Yablon S, Sherer M, Nick T, Ivanhoe C, Fellus J | view full details |
| Lead Center: | Methodist Rehabilitation Center | |
| Collaborating Centers: | The Institute for Rehabilitation and Research, Kessler Medical Rehabilitation Research and Education Corporation | |
| Pharmacotherapy of Symptoms of the Post-traumatic Confusional State among Neurorehabilitation Admissions with TBI: A Randomized, Double-blind, Placebo-controlled, (Parallel-group)Trial | ||
| Abstract: Patients with TBI who require inpatient rehabilitation are frequently confused at the time of admission for rehabilitation. Our investigations of confusion conducted as part of the TBIMSM have clarified the nature of confusion in early recovery after TBI. Early confusion (PTCS) has been found to be a complex syndrome characterized by disorientation, cognitive impairment, restlessness, decreased level of daytime arousal, sleep disturbance, fluctuation of symptoms, and psychotic-type symptoms. PTCS complicates early management of patients with TBI and may contribute to increased risk of injury to patients and hospital staff, increased stress among family members and staff, decreased participation in therapies, increased cost of care, and... more | ||
| Investigators: | Yablon S, Thompson R, Sherer M | view full details |
| Lead Center: | Methodist Rehabilitation Center | |
| Post-traumatic Confusion State after Traumatic Brain Injury | ||
| Abstract: The period of motoric agitation/withdrawal, disorientation, attention and memory deficits, mood lability, suspiciousness, and hallucinations that occurs after TBI has been called post-traumatic delirium (PTD) or post-traumatic amnesia (PTA). Recent research has indicated that confusion or attentional disturbance is the defining characteristic of this period rather than memory impairment. Our investigations have confirmed the similarity of this period of recovery to delirium and support the use of the term Post-traumatic Confusional State (PTCS) to describe this period. We have collected data on a substantial number of patients in PTCS. Our investigations have resulted in determination of 7 key symptoms of PTCS and the development of a... more | ||
| Investigators: | Sherer M, Yablon S, Thompson R | view full details |
| Lead Center: | Methodist Rehabilitation Center | |
| A Multicenter Prospective Randomized Controlled Trial of the Effectiveness of Amantadine Hydrochloride in Promoting Recovery of Function Following Severe Traumatic Brain Injury | ||
| Abstract: Severe traumatic brain injury may result in severe disorders of consciousness (DOC), including coma, the vegetative state (VS) and the minimally conscious state (MCS). The longer the duration of impaired consciousness, the worse the ultimate functional prognosis, with only about half of those individuals who remain unconscious for a month post-TBI regaining consciousness within a year. The severe functional disability associated with prolonged DOC places enormous emotional, financial, ethical, and logistical strains on caregivers and major resource demands on society. Numerous treatments have been recommended to hasten the return of consciousness or improve the ultimate level of recovery, including various psychotropic drugs, "coma... more | ||
| Investigators: | Giacino J, Whyte J, Kalmar K, Yablon S, Sherer M, Bagiella E, Murathe S, Singh V, Long D, Murphy E, Merges B, Eifert B, Mauer P, Katz D, Edelstein M, Novak P, Wright L, Van Wie S, Childs N, Mercer W | view full details |
| Lead Center: | JFK Johnson Rehabilitation Institute | |
| Collaborating Centers: | Moss Rehabilitation Research Institute, Methodist Rehabilitation Center | |
| Collaborative Study of Impaired Self-awareness after Traumatic Brain Injury (CSISATBI) | ||
| Abstract: The CSISATBI conducted the first large-scale, prospective longitudinal study of impaired self-awareness' (ISA) neural substrates, neuropsychological features, natural history, and relationship to functional and quality-of-life outcomes over the first year following moderate to severe TBI. Extensive data on self-awareness, injury characteristics, neuropsychological status, and various outcomes were collected on 177 persons with TBI. Three papers have already been published and additional papers are in progress. Findings published to this point show that impaired self-awareness is common after TBI and is a significant factor in influencing outcome from TBI. ... more | ||
| Investigators: | Sherer M, Hart T, Thompson R, Whyte J, Yablon S | view full details |
| Lead Center: | Methodist Rehabilitation Center | |
| Collaborating Centers: | Moss Rehabilitation Research Institute | |
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5 projects available at this time for Stuart A. Yablon, M.D.
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