Projects of the TBINDC Registry by Researchers Last Name
A Randomized Controlled Family Intervention Trial
Abstract: Family members will be recruited between 1 and 2 years after injury. Family members who agree to participate will be randomly assigned to either a cognitive-behavioral treatment group, a traditional support group, or a no treatment control group. Pre-test and post-test measures will be administered to assess family systems functioning, emotional distress, perceived burden, coping strategies, and satisfaction with social support... more
Investigators: Sander A, Sherer M, Malec J view full
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Lead Center: The Institute for Rehabilitation and Research
Collaborating Centers: Mayo Medical Center, Methodist Rehabilitation Center
Prediction of Patients' Progress in Post-Acute Rehabilitation Based on Family Environment at the Time of Admission
Abstract: The purpose of the current study is to determine the relationship of family functioning to patients' ability to complete a post-acute rehabilitation program, and to their outcome following participation in the program. Information on the family systems functioning and caregivers' distress will be collected within 2 weeks of admission to the program. Functional assessment of disability and handicap will take place within 2 weeks of admission and approximately 1 month after discharge. Regression models will be constructed to predict admit to discharge change scores from demographic characteristics, injury characteristics, and the family variables.
... more
Investigators: Sander A, Sherer M, Malec J view full
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Lead Center: The Institute for Rehabilitation and Research
Collaborating Centers: Mayo Medical Center, Methodist Rehabilitation Center
Prediction of Long-Term Patient Outcome Based on Pre-Injury Family Environment
Abstract: The purpose of the current study is to determine is the pre-injury family environment is predictive of the outcome of persons with TBI at 1 year after injury. Information on the pre-injury family environment, including emotional distress, coping, family systems functioning, and social support, will be collected within 2 weeks of admission to inpatient rehabilitation. Information on the outcome of persons with injury will be collected at 1 year post-injury. Regression models will be constructed to predict outcome from demographic characteristics, injury characteristics, and the pre-injury family environment.... more
Investigators: Sander A, Sherer M, Malec J view full
details
Lead Center: The Institute for Rehabilitation and Research
Collaborating Centers: Mayo Medical Center, Methodist Rehabilitation Center
Prediction of Long-Term Family Functioning Based on Pre-Injury Family Environment
Abstract: The current study will seek to characterize the pre-injury family environment of persons with TBI and to determine if the preinjury family environment can predict family members' response to TBI. Information on emotional distress, family systems functioning, social support, and coping styles in the month prior to injury will be obtained from family members within 2 weeks of admission to inpatient rehabilitation. These variables will be used to predict family adjustment at 1 year, after controlling for demographics and injury-related characteristics... more
Investigators: Sander A, Sherer M, Malec J view full
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Lead Center: The Institute for Rehabilitation and Research
Collaborating Centers: Mayo Medical Center, Methodist Rehabilitation Center
Early Cognitive Status and Productivity Outcome Following Traumatic Brain
Abstract: To evaluate the contribution of early cognitive assessment to prediction of productivity outcome after traumatic brain injury (TBI) adjusted for severity of injury, demographic factors, and pre-injury employment status. Design: Inception cohort. Setting: Six inpatient brain injury rehabilitation programs. Participants: 388 adults with TBI whose post-traumatic amnesia resolved prior to discharge from inpatient rehabilitation. Results: Multiple logistic regression analysis revealed that pre-injury productivity status, duration of post-traumatic amnesia, education level, and early cognitive status each made significant, independent contributions to prediction of productivity status at follow-up. Conclusions: Findings support the... more
Investigators: Sherer M, Sander A, Nick T, High Jr. W, Malec J, Rosenthal M view full
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Lead Center: Methodist Rehabilitation Center
Collaborating Centers: The Institute for Rehabilitation and Research, Mayo Medical Center, Kessler Medical Rehabilitation Research and Education Corporation
Effect of blood alcohol level on neurpsych outcome from TBI
Abstract: 1) To resolve contradictory reports in the literature regarding adverse effects of acute blood alcohol level (BAL) on neuropsychological outcome from traumatic brain injury (TBI). 2) 459 adults with nonpenetrating TBI who were inpatients at one of 6 rehabilitation centers in the TBI Model Systems project, whose BAL had been measured at hospital arrival, and who emerged from post-traumatic amnesia (PTA) and underwent neuropsychological testing before rehabilitation discharge. 3)15 neuropsychological tests were administered after resolution of post-traumatic amnesia and at one year post-injury. 4) BAL was classified as 1) negative vs. positive and 2) intoxicated (BAL > 100 mg/dl) vs. non-intoxicated. The effect of BAL on neuropsychological... more
Investigators: Boake C, High Jr. W, Sander A, Kreutzer J, Macciocchi S, Stringer A, Hammond F, Rosenthal M, Bogner J, Hanks R view full
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Lead Center: The Institute for Rehabilitation and Research
Collaborating Centers: Emory University/Shepherd Center, Ohio State University, Rehabilitation Institute of Michigan, Carolinas Rehabilitation, Kessler Medical Rehabilitation Research and Education Corporation, Virginia Commonwealth University/Medical College of Virginia
Subjective Well-being in the First Two Years Following Traumatic Brain Injury
Abstract: Purpose: Examine predictors of life satisfaction one and two years post-injury.

Design: Prospective, longitudinal study of patients with TBI followed at one and two years post-injury. Replication of a single center study using data from the TBI Model Systems dataset. Univariate regression models will be calculated first. Those variables
that account for at least 1% of variance will be included in subsequent stepwise linear regression models.

Current status: Data has been compiled.... more
Investigators: Corrigan J, Bogner J, Hammond F, Sander A, Whiteneck G, Kreutzer J view full
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Lead Center: Ohio State University
Collaborating Centers: Carolinas Rehabilitation, The Institute for Rehabilitation and Research, Virginia Commonwealth University/Medical College of Virginia
A Collaborative National Information Center on Outcome Measurement in Brain Injury
Abstract: In order to better serve the rehabilitation community, the Center on Outcome Measurement in Brain Injury (COMBI) website and newsletter are proposed. The COMBI provides information on measures in a format that is easily accessed and understood, free of charge, objective, and comprehensive. Each measure will have online syllabi, training and testing materials (including the measure's rating form), information on scale properties, a reference listing of published studies using the measure, and a section for "Frequently Asked Questions."... more
Investigators: Bushnik T, Wright J, Mellick D, Harrison-Felix C, Boake C, Sander A, Malec J, Sherer M, Thompson R, Novack T, Dijkers M, Bogner J, Corrigan J, Hammond F, Kreutzer J, Marwitz J, Millis S, O'Neil-Pirozzi T view full
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Lead Center: Santa Clara Valley Medical Center
Collaborating Centers: Craig Hospital, The Institute for Rehabilitation and Research, Mayo Medical Center, Methodist Rehabilitation Center, University of Alabama, Rehabilitation Institute of Michigan, Ohio State University, Carolinas Rehabilitation, Virginia Commonwealth University/Medical College of Virginia, Moss Rehabilitation Research Institute, Kessler Medical Rehabilitation Research and Education Corporation, Spaulding Rehabilitation Hospital, Mount Sinai School of Medicine



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